Is there a known risk of thromboembolic activity?

Tests on OMNI-STAT & Celox products have included examination of whether particles may enter the bloodstream, no evidence was found based on histologically examined tissue from the treated vessels in a swine model of lethal artery injury.7 Femoral artery injuries in ten swine were treated with Celox Gauze and these showed some granules on the outside of the treated vessel, as expected, but no particles inside the vessel walls. This is consistent with previous findings in other similar studies. Clay et al8 used an arterial catheter and showed diminished – but measurable – arterial pressure in the ipsilateral thigh, after treatment with Celox granules for extremity artery hemorrhage, indicating that circulation was not blocked. Kheirabadi9 also showed continued distal blood flow with Celox, even after the treated vessel was occluded by the treatment.

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